Life is not just a battle for significance, it is most importantly a battle of relevance. If you become irrelevant you will be ignored. If you get ignored you may end up discarded. This is the essence of creative destruction.
To say relevant:
1. Give value - make a difference to someone.
2. Keep your eyes open - study trends. See shifts in the market and in opinions.
3. Listen - do not only hear but listen to the voice of the customer.
4. Lead daily - never be content with yesterday's expertise or views. Keep upgrading your knowledge base.
5. Read my blog! I share what I learn and would be delighted to get your feedback so that also remain relevant.